Given the established needs of Children who are Affected and Infected by HIV/AIDS (CABA) and the conspicuous dynamic relations within Vietnamese society, the author proposed to research the following question: To what extent do the current relations among the Socialist Government of Vietnam (GO), Non-Governmental Organizations (NGOs), and International Development Organizations (IDOs) affect services provided to children who are affected and infected by HIV/AIDS in Ho Chi Minh City (HCMC), Vietnam. In order to study the inter-sectoral collaboration on HIV/AIDS children's issues in HCMC, a qualitative research approach was used. Interviews were conducted with a total forty-nine interviewees representing three sectors. The interviews were conducted in order to assess their state of relations and the effect those relations have on services for children with HIV/AIDS in Ho Chi Minh City. Adil Najam's conceptual framework of the Four C's of third sector- government relations: Cooperation, Confrontation, Complementarity, And Co-Optation (2000) was used as the framework of analysis for the stakeholder relations. Each sector's data was analyzed based on the eleven research questions related to the Four C's concept. The ratios of C percentages were compared sector to sector and then the statistical mean for each C in each sector was calculated. The data clearly demonstrates which Cs are dominant both within each sector and among all the sectors for addressing CABA issues. The author then explored why some common C themes in each group/sector present themselves and how the variations between the Four Cs reflect the different goals and means used by each sector to achieve a specific purpose.